Principles of prescribing in pregnancy

Medication use (both over the counter and prescribed) is common during pregnancy and lactation. However, prescribing in pregnancy can be challenging for several reasons. First, the physiological changes associated with pregnancy and its impact on the pharmacokinetics of medications. Second, the lack of information regarding potential adverse fetal effects of new medications. Adherence to the safe principles of prescribing together with patient involvement in decision making is essential when prescribing in pregnancy. In this article, we review the principles of safe prescribing in pregnancy and review commonly used medications and their potential teratogenic effects. Finally, we discuss the management of pregnancy complicated with potential teratogenicity.