| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8783748 | Reproductive BioMedicine Online | 2018 | 7 Pages |
Abstract
This study shows the value of sperm FISH analysis in improving genetic reproductive advice for IRI carriers. Disruption of critical genes through this rearrangement and their consequent functional impairment could result in recurrent miscarriages. In this case, several genes located in the 14q11.2 region, particularly RNase 3, would be good candidates to explain the lethality of the imbalances.
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Authors
Gaëlle Salaun, Andrei Tchirkov, Christine Francannet, Hanae Pons, Florence Brugnon, Celine Pebrel-Richard, Laetitia Gouas, Eleonore Eymard-Pierre, Philippe Vago, Carole Goumy,