Evaluation of thiol/disulphide homeostasis as a novel predictor testing tool of early pregnancy viability

Significantly increased serum disulphide levels, one of the oxidative stress markers, and decreased antioxidant levels (total and native thiol) were found in patients with MA. Increased oxidative stress status is thought to play a role in the etiology of MA. Serum dynamic thiol/disulphide homeostasis may serve as a promising testing tool to rule out subsequent diagnosis of MA and may benefit as an early pre-treatment testing tool for viability.