Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8784393 | Taiwanese Journal of Obstetrics and Gynecology | 2018 | 6 Pages |
Abstract
HMGB1 nuclear-cytoplasmic translocation in pPROM placenta may lead to the binding of HMGB1 to its receptor RAGE, resulting in provoking NF-κBp65 activity, and then inducing the release of MMP-9 and MMP-2, which all above activities contributed to the process of pPROM. Consequently, HMGB1-RAGE signaling pathway may be involved in the pathogenesis of pPROM.
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Authors
Huan Yan, Linlin Zhu, Zhan Zhang, Hong Li, Pengyun Li, Yan Wang, Maodong Leng,