Preliminary preventive protocol from first trimester of pregnancy to reduce preterm birth rate for dichorionic-diamniotic twins

Even though this was a preliminary study, the results are promising, and we propose custom-made management for dichorionic-diamniotic twins: (1) earlier management from before 14 weeks; (2) high-risk selection for cervicitis and a short cervix; and (3) intervention with anti-inflammatory agents and cerclage if indicated.