Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8785536 | Bulletin du Cancer | 2018 | 6 Pages |
Abstract
Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, are multifactorial diseases characterized by a chronic intestinal inflammation. Abdominal and pelvic irradiation can result in acute or chronic digestive toxicity. A few old studies on small population samples have suggested an increase of gastro-intestinal toxicities in patients with IBD in case of irradiation. Nevertheless, the physiopathology is unknown. More recent studies, including new irradiation techniques, have shown less toxicity events in these patients with IBD. There are no recommendations for irradiation in patients with IBD. This review aims to report recent data on this topic and discuss them regarding radiation parameters.
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Authors
Omar Jmour, Anna Pellat, Laurianne Colson-Durand, Nhu Hanh To, Igor Latorzeff, Paul Sargos, Iradj Sobhani, Yazid Belkacemi,