| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8785749 | Cancer Treatment and Research Communications | 2018 | 21 Pages |
Abstract
A two-Stage Genome wide association study in Caucasian population reveals germline genetic variation in SMYD2 associated to progression disease in first-line platinum-based treatment in advanced NSCLC patients. SMYD2 profiling might have prognostic / predictive value directing choice of therapy and enlighten current knowledge on pathways involved in human carcinogenesis as well in resistance to chemotherapy.
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Authors
Iván Galván-FemenÃa, Marta Guindo, Xavier Duran, SÃlvia Calabuig-Fariñas, Josep Maria Mercader, Jose Luis Ramirez, Rafael Rosell, David Torrents, Anna Carreras, Takashi Kohno, Eloisa Jantus-Lewintre, Carlos Camps, Manuel Perucho, Lauro Sumoy,