Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8786640 | European Journal of Surgical Oncology (EJSO) | 2018 | 16 Pages |
Abstract
The extent of lymphadenectomy for esophageal adenocarcinoma remains controversial. Outstanding issues include the appropriate technical approach such as transthoracic versus transhiatal, or open versus minimally invasive, both of which have implications on overall lymph node harvest numbers and morbidity. Recent data on the relationship of total number of lymph nodes harvested and oncologic survival have been conflicting, due in part to a likely differential impact of lymphadenectomy on survival based on tumor stage and response to neoadjuvant therapy. While standardizing the extent of lymphadenectomy may be desirable, a more useful approach might be to tailor lymphadenectomy considering the multidimensional impact of surgical technique and multimodal treatment strategy.
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Authors
Thomas C. Tsai, Jordan Miller, Ciro Andolfi, Brian Whang, P. Marco Fisichella,