Article ID Journal Published Year Pages File Type
8786692 European Journal of Surgical Oncology (EJSO) 2018 23 Pages PDF
Abstract
PIPAC leads to a significant chemotherapy uptake in both ascites and peritoneum, suggesting a bimodal cytotoxic effect of PIPAC via direct tissue uptake into peritoneal tumor nodules and via ascites. Consecutive PIPAC applications lead to peritoneal accumulation of doxorubicin, suggesting a cumulative cytotoxic effect of doxorubicin after repeated PIPACs.
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Health Sciences Medicine and Dentistry Oncology
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