Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8786692 | European Journal of Surgical Oncology (EJSO) | 2018 | 23 Pages |
Abstract
PIPAC leads to a significant chemotherapy uptake in both ascites and peritoneum, suggesting a bimodal cytotoxic effect of PIPAC via direct tissue uptake into peritoneal tumor nodules and via ascites. Consecutive PIPAC applications lead to peritoneal accumulation of doxorubicin, suggesting a cumulative cytotoxic effect of doxorubicin after repeated PIPACs.
Keywords
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Authors
Clemens B. Tempfer, Ziad Hilal, Askin Dogan, Miriam Petersen, Günther A. Rezniczek,