Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8787307 | Gaceta Mexicana de Oncología | 2016 | 4 Pages |
Abstract
The medullary thyroid carcinoma (MTC) is an unusual malignant neoplasm with a high rate of metastasis. It usually appears as a single nodule in more than 70% of the cases, and the main distant metastasis sites are liver, lung, and bone. Breast metastasis is rare because within the mammary tumours only between 0.2% and 1.3% are secondary tumours. MTC is strongly associated with the multiple endocrine neoplasia sub-type 2B (MEN2B), which is a dominant autosomal disorder characterised by the presence of MTC and phaeochromocytoma in the absence of hyperparathyroidism. Metastasis from a MTC to the breast in the context of a MEN2B rarely occurs, which is why this case is being reported.
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Authors
Lorenzo D'Angelo-Piaggio, Jose Echecopar-Sabogal, Diego M. Chanamé-Baca, Alberto Teruya-Gibu,