Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8787562 | Journal of Thoracic Oncology | 2018 | 27 Pages |
Abstract
Expression of PD-L2 is induced intrinsically by activating EGFR mutations or EML4-ALK fusion and extrinsically by IFN-γ, with STAT3 and c-FOS possibly contributing to both intrinsic and extrinsic pathways. Our results thus provide insight into the complexity of tumor immune escape in NSCLC.
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Authors
Daisuke MD, Kentaro MD, PhD, Eiji MD, PhD, Naoki MD, PhD, Keiichi MD, PhD, Koichi MD, PhD, Taishi MD, PhD, Jiro MD, PhD, Yoichi MD, PhD, Isamu MD, PhD,