Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8787874 | Journal of Thoracic Oncology | 2017 | 27 Pages |
Abstract
The mechanisms of primary resistance to EGFR TKIs may be highly heterogeneous. Mutations in EGFR and its downstream pathway, as well as mutations that affect tumor cell function, are related to primary resistance. Somatic single-nucleotide mutation patterns might be associated with primary resistance to EGFR TKIs.
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Authors
Jia MD, Lei MS, Zhijie MD, Hua PhD, Fei MS, Jianchun MD, Jun MD, Minglei MD, Yuyan MD, Shuhang MD, Wanchun MS, Meina MD, Tongtong MD, Guanhua PhD, Guanshan PhD, Jie MD, PhD,