Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8789325 | Practical Radiation Oncology | 2017 | 36 Pages |
Abstract
Intensity modulated radiation therapy (IMRT) has not yet been reported as a pulsed reduced dose rate (PRDR) delivery technique for recurrent brain tumors and may allow for safe and comprehensive reirradiation for large volume tumors. We reviewed our IMRT PRDR outcomes and toxicity and reviewed the literature of available PRDR series for recurrent central nervous system tumors. We conclude that IMRT PRDR reirradiation is a feasible and appropriate treatment strategy for large volume recurrent brain tumors resulting in acceptable overall survival with reasonable toxicity in our patients who were heavily pretreated.
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Authors
Erin S. MD, Kevin MS, Andrew PhD, Peng PhD, Chandana A. MSc, Manmeet S. MD, David M. MD, Glen H. DO, PhD, Jennifer S. MD, PhD, Rupesh MD, John H. MD, Samuel T. MD,