Carcinoma metaplásico escamoso primario de mama: un subtipo infrecuente. A propósito de tres casos en el Hospital Universitario del Caribe

Ductal carcinomas are the most common of all breast malignancies, less than 5% are of metaplastic nature, and 0.04% to 0.1% have squamous cell differentiation. These special subtypes are considered more aggressive. Due to the few cases in the literature, there is no consensus about its diagnosis and treatment. Three cases are presented with this diagnosis, seen in our institution between 2014 and 2015. They were women of 57, 49, and 65 years old with no risk factors, and who presented with similar clinical features, consisting of the appearance of a rapid growing mass. Two of the patients had been previously diagnosed with infiltrating ductal carcinoma of no special type by core needle biopsy, with a definitive diagnosis in radical mastectomy, which reported squamous metaplastic carcinoma confirmed by immunohistochemistry.