Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8790471 | American Journal of Ophthalmology | 2018 | 25 Pages |
Abstract
Visible on OCT, the ELM descent is a histopathologic atrophy border supporting new terminology of cRORA, whereas hypertransmission reveals RPE degeneration. RPE-BLamD thickening across the macula, toward the atrophy and over time is confirmed. The presence of gliosis and thick RPE-BLamD suggests that macular atrophy is a late stage in disease progression, encouraging anatomic endpoints at earlier AMD stages than atrophy enlargement.
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Authors
Rosa Dolz-Marco, Chandrakumar Balaratnasingam, Jeffrey D. Messinger, Miaoling Li, Daniela Ferrara, K. Bailey Freund, Christine A. Curcio,