Genetic Risk Score Is Associated with Vertical Cup-to-Disc Ratio and Improves Prediction of Primary Open-Angle Glaucoma in Latinos

Article ID	Journal	Published Year	Pages	File Type
8793853	Ophthalmology	2018	7 Pages	PDF

Abstract

To our knowledge, we identified a novel association between GRS and VCDR and its improvement in the discriminatory ability of POAG in a Latino population.

Keywords

VCDR SBP ROC CCT iOp POAG GRs AUC body mass index BMI central corneal thickness systolic blood pressure Intraocular pressure area under the receiver operating characteristic curve Genome-wide association study GWAS odds ratio vertical cup-to-disc ratio genetic risk score Single nucleotide polymorphism SNP primary open-angle glaucoma receiver operating characteristic