| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8793863 | Ophthalmology | 2018 | 11 Pages |
Abstract
The SNP rs3753396 in CFH and SNP rs6685931 in CFHR4 are associated with systemic complement activation levels. The SNP rs6685931 in CFHR4 and its linked haplotype H1-2 also conferred a risk for AMD development, and therefore could be used to identify AMD patients who would benefit most from complement-inhibiting therapies.
Keywords
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Authors
Laura MSc, Constantin C. MSc, Jordi PhD, Marc MSc, Maartje J. MSc, Lebriz MD, Tina MD, Mohamed R. PhD, Sascha MD, PhD, Carel B. MD, PhD, Anneke I. PhD, Eiko K. PhD,