| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8794054 | Ophthalmology | 2018 | 10 Pages |
Abstract
The association of the SNP at the ARMS2/HTRA1 locus with subretinal/sub-RPE hemorrhage and poorer visual acuity and of SNPs at the CFH locus with drusen area may provide new insights in pathophysiological pathways underlying different stages of AMD.
Keywords
RPEICD9PheWASComparison of Age-related Macular Degeneration Treatment TrialsCATTETDRSAMDCNVChoroidal neovascularizationgeographic atrophyretinal pigment epithelialage-related macular degenerationLinkage disequilibriumconfidence intervalVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)Genome-wide association studyGWASodds ratioSingle nucleotide polymorphismSNP
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Authors
Freekje MD, PhD, Michael MD, Ayush PhD, Tiarnan D. PhD, FRCOphth, Rinki PhD, Elvira MA, Traci E. PhD, Anand PhD, Zhiyong PhD, Emily Y. MD, Age-Related Eye Disease Study 2 Research Group Age-Related Eye Disease Study 2 Research Group,