| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8794714 | Ophthalmology Retina | 2018 | 7 Pages |
Abstract
Despite a decrease in VEGF-A, the aqueous levels of VEGF-C, angiopoietin 2, endothelin 1, follistatin, HB-EGF, HGF, and interleukin 8 increased significantly after intravitreal injection of bevacizumab. These upregulated angiogenic biomarkers may represent new therapeutic targets in exudative AMD.
Keywords
HGFIVBBMP-9PlGFBCVAEGFHB-EGFGCSFFGFCNVCrtAMDChoroidal neovascularizationMacular volumespectral-domainTIMPage-related macular degenerationmacular thicknesscentral retinal thicknessepidermal growth factorplacental growth factorHepatocyte growth factorVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)heparin-binding epidermal growth factor-like growth factorTissue inhibitor of metalloproteinases
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Authors
Thiago MD, Luiz H. MD, Luiz Guilherme MD, Júlia MD, Ãverton MD, Akiyoshi MD, PhD, Jimmy BS, MPH, Pedro MD, PhD, Caio V. MD, PhD, Vinit B. MD, PhD, Rubens MD, PhD,