Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8795157 | Revista Mexicana de Oftalmología | 2016 | 4 Pages |
Abstract
Lowe syndrome is an infrequent condition that affects several organs including the brain, kidneys and eyes inherited in an X-linked pattern. The most frequent abnormalities found are psychomotor retardation, Fanconi's syndrome and congenital cataracts and glaucoma. Enzymatic and molecular tests are available for confirmation of the diagnosis and for prenatal detection of the disease. The treatment includes: cataract extraction, glaucoma control, physical and speech therapy, use of drugs to address behavioural problems, and correction of the tubular acidosis and the bone disease with the use of bicarbonate, phosphate and potassium. Life span rarely exceeds 40 years. We present a case of Lowe's syndrome with renal abnormalities, bilateral cataracts and glaucoma, which were treated by trabeculectomy with mitomicin-C and lensectomy with anterior vitrectomy. It is important to acknowledge the potentially lethal repercussions to initiate an early multidisciplinary treatment.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Ophthalmology
Authors
Nadia Luz Casillas-ChavarÃn, Victor Manuel Villar-Calvo, Alfredo Lizárraga-Corona,