| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8800409 | Journal of Orthopaedic Science | 2017 | 7 Pages |
Abstract
ALN prevented ovariectomy-induced bone loss and mechanical hyperalgesia in hindlimbs, and it suppressed TRPV1 and CGRP expressions in DRG neurons. The results suggest that bone resorption with upregulation of TRPV1 and CGRP expressions is one of the causes of postmenopausal osteoporotic pain.
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Authors
Yohei Naito, Hiroki Wakabayashi, Sho Kato, Taro Nakagawa, Takahiro Iino, Akihiro Sudo,