Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8807344 | Diagnostic Histopathology | 2017 | 13 Pages |
Abstract
The pathologist's task is to provide the correct diagnosis and, when dealing with a genetic disease, to initiate pre-symptomatic cardiologic and genetic cascade screening of first-degree family members. Early identification is important because SD can be the first and last clinical presentation of the underlying disease and the only medical examination undertaken is the autopsy. A standardized and detailed post-mortem procedure on the SD victims, in combination with molecular testing (“molecular autopsy”), will provide vital information for the family in preventing a further tragedy. Therefore proper sampling to allow post-mortem DNA analysis as well as accurate morphological evaluation, are mandatory, as recommended in the guidelines for autopsy investigation of SD from the Association for European Cardiovascular Pathology.
Related Topics
Health Sciences
Medicine and Dentistry
Pathology and Medical Technology
Authors
Stefania Rizzo, Gaetano Thiene, Elisa Carturan, Kalliopi Pilichou, Cristina Basso,