Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8808011 | Revista Española de Patología | 2018 | 7 Pages |
Abstract
Small cell carcinoma of ovary-hypercalcemic type is an undifferentiated carcinoma. We describe two cases in women aged 32 and 29. Both presented with large masses and complete surgical extirpation was impossible. Histologically, the images were similar, with diffuse cell proliferation, accompanied by the presence of follicle-like spaces. In both cases it was necessary to make a differential diagnosis with entities such as adult or juvenile granulosa cell tumour, small cell carcinoma of pulmonary type, dysgerminoma and even peripheral neuroectodermal tumour. The absence of SMARCA4/BRG1 immunostaining proved very useful in the diagnosis of hypercalcemic small cell ovarian carcinoma.
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Authors
Gema Ruiz-GarcÃa, M. Amparo Torroba-Carón, Belén Ferri-ÃÃguez, Miriam Lencina-Guardiola, Francisco GarcÃa-Molina, Enrique MartÃnez-Barba,