Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8811118 | Journal of Pediatric Surgery Case Reports | 2017 | 4 Pages |
Abstract
Alveolar soft part sarcoma (ASPS) represents <1% of all soft tissue sarcomas and harbors the ASPSCR1-TFE3 translocation, which is found in pediatric renal cell carcinomas arising after chemotherapy. We present the case of a female patient, treated for metastatic retinoblastoma (Rb) with surgery, radiation, and chemotherapy at age 21 months, who was diagnosed with ASPS of the bladder 5 years later when imaging revealed a polypoid mass arising from the left bladder wall. Endoscopic biopsy and tumor resection were performed. After histopathologic confirmation of ASPSCR1-TFE3 fusion-positive ASPS, negative margins were achieved with wide local excision. At 18 months post-surgery, she remains recurrence-free.
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Authors
Daniel S. Rhee, Ira J. Dunkel, Neerav N. Shukla, Michael F. Walsh, Stephen W. Gilheeney, Anita P. Price, Cristina R. Antonescu, Todd E. Heaton,