Risk association of congenital anomalies in patients with ambiguous genitalia: A 22-year single-center experience

Patients with ambiguous genitalia often have additional congenital anomalies. Establishment of a specific diagnosis is uncommon in 46,XY patients. A few patients have gender reassignment outside of the newborn period. Ongoing collection of clinical data on this population may reveal new information regarding long-term health, quality of life, and establishment of more diagnoses with improved molecular techniques.136Figure. Flow chart of patients with ambiguous genitalia.