Article ID Journal Published Year Pages File Type
8811613 Journal of Pediatric Urology 2018 19 Pages PDF
Abstract
A significant proportion of children with MNE and normal MVV during the daytime frequently experienced wet nights, with a NUP well below their MVV and even <65% of EBC. This indicated that bladder reservoir dysfunction during sleep is relatively common in MNE. This abnormality was not reflected on daytime recordings, and thus nighttime data with NUP must be collected. This phenomenon may explain treatment failure to desmopressin, despite adequate antidiuretic response.133Figure. Number of desmopressin responders (%) in the three groups of patients. Patients were defined as frequently reduced eNBC if >40% of wet nights were with NUP 
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