| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8812128 | The Journal of Pediatrics | 2018 | 10 Pages |
Abstract
This study provides strong evidence that treatment of obstructive sleep apnea/nocturnal hypoxia with CPAP in children with NAFLD may reverse parameters of liver injury and reduce oxidative stress. These data also suggest CPAP as a new therapy to prevent progression of NAFLD in those children with obesity found to have obstructive sleep apnea/nocturnal hypoxia.
Keywords
NAFLDPDSSHDLSao2ALTNASaHICPAPASTAspartate aminotransferaseAlanine aminotransferaseSleep apneanonalcoholic steatohepatitisNonalcoholic fatty liver diseaseapnea/hypopnea indexbody mass indexBMIContinuous positive airway pressurehigh-density lipoprotein cholesterolNAFLD activity scoreNash HypoxiaC-reactive proteinCRPReactive oxygen species
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Authors
Shikha S. MD, MSCI, Ann C. MD, Jelena PhD, Zhaoxing PhD, Kristen BS, Kelley E. MD, Ronald J. MD,