Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8813874 | Biological Psychiatry | 2018 | 54 Pages |
Abstract
ASD-PTEN mutations display decreased stability, catalytic activity, and/or altered subcellular localization. Mutations lacking nuclear localization uncover a novel mechanism whereby lipid phosphatase activity in the nucleus can regulate mammalian target of rapamycin signaling and neuronal growth.
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Authors
Catherine J. Fricano-Kugler, Stephanie A. Getz, Michael R. Williams, Ashley A. Zurawel, Tyrone Jr., Paul W. Frazel, Meijie Li, Alistair J. O'Malley, Erika L. Moen, Bryan W. Luikart,