| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8813891 | Biological Psychiatry | 2018 | 51 Pages |
Abstract
Gpr88 deletion disrupts executive, reward, and emotional networks in a configuration that reduces alcohol reward and promotes alcohol seeking and drinking. The functional connectivity signature is reminiscent of alterations observed in individuals at risk for AUD. The Gpr88 gene, therefore, may represent a vulnerability/resilience factor for AUD, and a potential drug target for AUD treatment.
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Biological Psychiatry
Authors
Sami Ben Hamida, Sueli Mendonça-Netto, Tanzil Mahmud Arefin, Md. Taufiq Nasseef, Laura-Joy Boulos, Michael McNicholas, Aliza Toby Ehrlich, Eleanor Clarke, Luc Moquin, Alain Gratton, Emmanuel Darcq, Laura Adela Harsan, Rafael Maldonado,