Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8813928 | Biological Psychiatry | 2018 | 10 Pages |
Abstract
These results showed that antidepressants protected synaptic plasticity and neuronal circuitry from the effects of stress via a modulation of Ca2+ channels and synaptic plasticity independent of SERT. Thus, L-type Ca2+ channels might constitute an important signaling hub for stress response and for pathophysiology and treatment of depression.
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Authors
Claus Normann, Sibylle Frase, Verena Haug, Gregor von Wolff, Kristin Clark, Patrick Münzer, Alexandra Dorner, Jonas Scholliers, Max Horn, Tanja Vo Van, Gabriel Seifert, Tsvetan Serchov, Knut Biber, Christoph Nissen, Norbert Klugbauer,