| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8813945 | Biological Psychiatry | 2018 | 69 Pages |
Abstract
Our results highlight a differential role of serotonergic projections arising from the MRN and DRN in the regulation of cocaine intake. We propose that a cocaine-induced shift from MRN-driven serotonergic control of CRF levels in the hypothalamus to DRN-driven serotonergic control of CRF levels in the amygdala may contribute to the transition from moderate to compulsive intake of cocaine.
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Biological Psychiatry
Authors
Michel M.M. Verheij, Candice Contet, Peter Karel, Judith Latour, Rick H.A. van der Doelen, Bram Geenen, Josephus A. van Hulten, Francisca Meyer, Tamas Kozicz, Olivier George, George F. Koob, Judith R. Homberg,