Article ID Journal Published Year Pages File Type
8814164 Biological Psychiatry 2018 12 Pages PDF
Abstract
We provide evidence that maternal immune activation hits a key neurodevelopmental process, the excitatory-to-inhibitory gamma-aminobutyric acid switch; defects in this switch have been unequivocally linked to diseases such as autism spectrum disorder or epilepsy. These data open the avenue for a safe pharmacological treatment that may prevent the neurodevelopmental defects caused by prenatal immune activation in a specific pregnancy time window.
Related Topics
Life Sciences Neuroscience Biological Psychiatry
Authors
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