Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8814227 | Biological Psychiatry | 2018 | 59 Pages |
Abstract
These findings suggest a dual mechanism of white matter vulnerability in Huntington's disease, in which abnormal transcription of synaptic genes and metabolic disturbance not related to transcription may drive white matter loss.
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Authors
Peter McColgan, Sarah Gregory, Kiran K. Seunarine, Adeel Razi, Marina Papoutsi, Eileanoir Johnson, Alexandra Durr, Raymund A.C. Roos, Blair R. Leavitt, Peter Holmans, Rachael I. Scahill, Chris A. Clark, Geraint Rees, Sarah J. Tabrizi,