Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8815820 | Journal of Affective Disorders | 2018 | 23 Pages |
Abstract
The results suggest that HTR1A/1B DNA hypomethylation and its interaction with recent life stress might drive impaired antidepressant treatment response. Meanwhile, DNA methylation, in turn, was modified by antidepressant treatment and environments. Our results offer new evidence for the role of epigenetic and genetic polymorphism in pharmacological response to antidepressants.
Related Topics
Health Sciences
Medicine and Dentistry
Psychiatry and Mental Health
Authors
Peipei Wang, Qinyu Lv, Yemeng Mao, Cuizhen Zhang, Chenxi Bao, Hong Sun, Hanmei Chen, Zhenghui Yi, Weimin Cai, Yiru Fang,