| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8817510 | Biomedical and Environmental Sciences | 2017 | 4 Pages |
Abstract
Twelve healthy rats were divided into the T-2 toxin group receiving gavage of 1 mg/kg T-2 toxin and the control group receiving gavage of normal saline. Total relative concentrations of T-2 toxin and HT-2 toxin in the skeletal system (thighbone, knee joints, and costal cartilage) were significantly higher than those in the heart, liver, and kidneys (P < 0.05). The relative concentrations of T-2 toxin and HT-2 toxin in the skeletal system (thighbone and costal cartilage) were also significantly higher than those in the heart, liver, and kidneys. The rats administered T-2 toxin showed rapid metabolism compared with that in rats administered HT-2 toxin, and the metabolic conversion rates in the different tissues were 68.20%-90.70%.
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Authors
Fang Fang YU, Xia Lu LIN, Lei YANG, Huan LIU, Xi WANG, Hua FANG, Mikko J. LAMMI, Xiong GUO,