| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8818216 | Journal of Traditional Chinese Medicine | 2017 | 9 Pages |
Abstract
Mahuang (Herba Ephedra Sinica) and Wuweizi (Fructus Schisandrae Chinensis) can promote AM and IM migration ability, with Mahuang (Herba Ephedra Sinica) targeting AM more apparently and Wuweizi (Fructus Schisandrae Chinensis) targeting IM more apparently. The mechanism may be that, by stimulating cells, Mahuang (Herba Ephedra Sinica) and Wuweizi (Fructus Schisandrae Chinensis) promote expression of CCR2 and CCR5 receptors on the AM and IM cell surface, which pass signals to Kvl.3 and Kvl.5 ion channels, leading to changes in the cytoskeleton, and ultimately promoting chemotactic cell migration.
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Authors
Yuan Yiping, Zhai Huaqiang, Zhang Tian, Guo Zhaojuan, Kong Liting, Jia Xiaoyu, Wang Ning-ning, Dai Ying, Liu Guoxiu, Wang Yanping,