Comparison of ex vivo and in vitro intestinal cystic fibrosis models to measure CFTR-dependent ion channel activity

Article ID	Journal	Published Year	Pages	File Type
8819600	Journal of Cystic Fibrosis	2018	9 Pages	PDF

Keywords

ICM CFTR Fsk forskolin NKCC1 ISC CCH GAPDH HBE LGR5 FIS leucine-rich repeat-containing G-protein coupled receptor 5 IBMX Organoids IEQ 3-isobutyl-1-methylxanthine cyclic AMP AUC cAMP DMSO ENaC amiloride periodic acid-Schiff Electrophysiology Biopsies Differentiation Monolayers HIS Dimethylsulfoxide cystic fibrosis transmembrane conductance regulator Human bronchial epithelial cells Cystic fibrosis Short-circuit current Transepithelial resistance not significant Area-under-the-curve PAS wild type Histamine Carbachol epithelial sodium channel glyceraldehyde 3-phosphate dehydrogenase

Related Topics

Health Sciences Medicine and Dentistry Pulmonary and Respiratory Medicine

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Comparison of ex vivo and in vitro intestinal cystic fibrosis models to measure CFTR-dependent ion channel activity

Authors

Domenique D. Zomer-van Ommen, Eyleen de Poel, Evelien Kruisselbrink, Hugo Oppelaar, Annelotte M. Vonk, Hettie M. Janssens, Cornelis K. van der Ent, Marne C. Hagemeijer, Jeffrey M. Beekman,