Enhanced CD8+ cytolytic T cell responses in the peripheral circulation of patients with sarcoidosis and non-Löfgren's disease

Article ID	Journal	Published Year	Pages	File Type
8819933	Respiratory Medicine	2018	7 Pages	PDF

Abstract

These results demonstrated enhanced peripheral CD8+ CTL responses in sarcoidosis, especially in non-LS patients who have an increased risk of chronic disease. Further comprehensive clinical studies are warranted to increase our understanding of CD8+ CTL responses in sarcoidosis.

Keywords

Granzyme B T helper cytolytic T cell M. tuberculosis PBL BAL TIM Phytohemagglutinin TCr PHA CTL PBMC TNF FBS Löfgren's syndrome BHL FACS WASOG Human leukocyte antigen HLA interferon IFN interleukin Tuberculosis fluorescence-activated cell sorting Sarcoidosis fetal bovine serum Peripheral blood mononuclear cell tumor necrosis factor bronchoalveolar lavage peripheral blood lymphocytes Mycobacterium tuberculosis Perforin Chromium granulysin T cell receptor

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Enhanced CD8+ cytolytic T cell responses in the peripheral circulation of patients with sarcoidosis and non-Löfgren's disease

Authors

Venkata Ramanarao Parasa, Helena Forsslund, Tobias Enger, Daniel Lorenz, Susanna Kullberg, Anders Eklund, Magnus Sköld, Jan Wahlström, Johan Grunewald, Susanna Brighenti,