Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8823805 | Journal of Vascular and Interventional Radiology | 2018 | 10 Pages |
Abstract
This study successfully validated a protocol to develop METAVIR F3-F4 fibrosis within 8 weeks in the OCM, supporting its potential to serve as a model for hepatocellular carcinoma in a fibrotic liver background. Further investigation is required to determine if repeated alcohol liver injury is required to develop an irreversible METAVIR grade F4 porcine cirrhosis model.
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Authors
Ron C. MD, Nasya BS, Daniel P. DVM, PhD, Kelly D. DVM, PhD, R. Peter MD, MPH, Regina M. BS, Michael DVM, Faith M. BS, Lauretta A. PhD, Lawrence B. PhD, Kyle M. PhD,