| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8826931 | Transplantation Proceedings | 2018 | 6 Pages |
Abstract
DGF affects the fate of a graft. Within a several months after transplantation, TLR4ex of peripheral blood mononuclear cells declines in DGF patients. Low LR4ex in patients with DGF+ is associated with poor prognosis for the efficiency of the KT. In patients with DGF+, the proper selection of immunosuppression (tacrolimus dosing) is very important. Higher concentrations of tacrolimus may improve prognosis. The analysis of TLR4ex change may be a useful parameter for the real assessment of immunosuppression efficacy. It is important for transplanted organ function that peripheral blood mononuclear cells effectively leave circulation and remain in the graft.
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Authors
S. Zmonarski, K. Madziarska, M. Banasik, O. Mazanowska, M. Magott-Procelewska, K. Hap, M. Krajewska,