| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8827071 | Transplantation Proceedings | 2018 | 6 Pages |
Abstract
Our results reveal that miR-449a microRNA was elevated in allogeneic heart allografts. This correlated with an increased miR-449a expression in activated CD4+ T cells. Inhibition of miR-449a in activated CD4+ T cells coincided with reduced mitochondrial respiration, suggesting that miR-449a influences CD4+ T-cell activation during the alloimmune response by regulating metabolic status.
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Authors
L. Huang, F. Li, Q. Fu, X. Yang, S. Deng, L. Wei,