Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8830152 | Urology Practice | 2018 | 23 Pages |
Abstract
This systematic review summarizes the existing literature on the use of antifibrotic drugs for urological disease. Safety, efficacy and long-term outcomes for each drug are evaluated for various disease types and current recommendations for use are reviewed. This systematic review also details the potential therapeutic roles of several antifibrotic medications for treating common urological conditions and diseases, showing that they can be important, useful and effective additions to the urologist's armamentarium.
Keywords
RCTTGF-βFDAAUABNCMitomycin CECMinfCCHMMCRandomized controlled trialAmerican Urological AssociationBladder neck contractureinterferonPeyronie’s diseaseUrologic diseasestransforming growth factor-βTriamcinolone acetonideFood and Drug AdministrationFibrosisExtracellular matrixUrethral stricturesTreatment outcome
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Authors
Omer A. Raheem, Yash S. Khandwala, Tung-Chin Hsieh, Jill C. Buckley,