Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8833411 | Journal of the American College of Surgeons | 2018 | 25 Pages |
Abstract
The gene BCL9 is overexpressed in malignant adrenocortical tumors and promotes clonal ACC cell growth. These findings suggest that BCL9 overexpression may serve as an alternative driver of constitutive Wnt/β-Catenin activation in ACC and could represent a potential molecular and diagnostic marker of tumor malignancy.
Keywords
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Authors
Taylor C. MD, MHS, Norman G. MD, Reju PhD, Tobias MD, PhD, FACS,