Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8833722 | Journal of the American College of Surgeons | 2018 | 30 Pages |
Abstract
Carriers of BRCA1/BRCA2 mutation with sporadic PDAC had a worse survival after pancreatectomy than their BRCA wild-type counterparts. However, platinum-based chemotherapy regimens were associated with markedly improved survival in patients with BRCA1/BRCA2 mutations, with survival differences no longer appreciated with wild-type patients.
Keywords
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Surgery
Authors
Alex B. MD, Vincent P. MD, Georgios MD, Jishu MD, PhD, John L. MD, FACS, Matthew J. MD, FACS, Michael MD, Christopher L. MD, PhD, FACS, Jun MD, PhD, Jin MD, PhD, FACS,