Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8835260 | Journal of Surgical Research | 2018 | 8 Pages |
Abstract
Microfluidic coagulation assessment with T-TAS has an overall poor correlation with most TEG measurements in a predominantly hypercoagulable patient population, except in the presence of t-PA. The one anticipated finding was an elevated MA having a shorter time to platelet-mediated microfluidic occlusion, supporting the role of platelets and hypercoagulability. However, hypercoagulability defined by LY30 had opposing results in which a low LY30 was associated with a longer PL time to occlusion and slower OSp. These discordant findings warrant ongoing investigation into the relationship between clot strength and fibrinolysis under different flow conditions.
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Authors
Peter J. BA, Hunter B. MD PhD, Ernest E. MD, Mark E. MD, Gregory R. MD, Anirban PhD, Richard D. MD MBA, Trevor L. MD,