Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8835288 | Journal of Surgical Research | 2018 | 10 Pages |
Abstract
Collectively, these pilot data in a model of CDH lung hypoplasia suggest a primary aberration in response to mechanical stress within the nitrofen lung, characterized by an upregulation of ACTA2 and a downregulation in SPFTC and POSTN. This ex vivo compression system may serve as a novel research platform to better understand the mechanobiology and complex regulation of matricellular dynamics during CDH fetal lung development.
Keywords
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Surgery
Authors
Zachary D. BA, Guihua MS, Kenneth K.Y. BE, Kendal A. BS, Allen P. PhD, Shaun M. MD, MSc,