Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8835316 | Journal of Surgical Research | 2018 | 9 Pages |
Abstract
DEL1 protected chondrocytes from apoptosis in response to activators of either the intrinsic or extrinsic pathways, and to anoikis. This effect was mediated primarily through integrin αVβ3. This represents a therapeutic target for therapies to prevent cartilage degeneration in OA.
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Authors
Zhen MD, Tatiana MD, Misha C. BA, Marie BS, Namrata BS, Vania MD, Michael T. MD, MBA, George P. MD, PhD,