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α7 Nicotinic acetylcholine receptor contributes to the alleviation of lung ischemia-reperfusion injury by transient receptor potential vanilloid type 1 stimulation

Article ID Journal Published Year Pages File Type
8835391 Journal of Surgical Research 2018 11 Pages PDF
Abstract
TRPV1 activation alleviates LIRI, partially dependent on α7nAChR activity. The α7nAChR stimulation with or without existence of TRPV1 alleviates LIRI. Thus, α7nAChR is involved in the pathway of TRPV1-mediated protection against LIRI and the specific mechanism remains to be revealed.
Keywords
alpha-7 nicotinic acetylcholine receptorLung injuryIschemiaApoptosisReperfusionTransient receptor potential vanilloid 1
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Health Sciences Medicine and Dentistry Surgery
Preview
α7 Nicotinic acetylcholine receptor contributes to the alleviation of lung ischemia-reperfusion injury by transient receptor potential vanilloid type 1 stimulation
Authors
Xuehan PhD, Yi MD, Yan BD, Rurong MD, PhD,
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Journal of Surgical Research
Journal: Journal of Surgical Research
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