Article ID Journal Published Year Pages File Type
8835560 Journal of Surgical Research 2018 13 Pages PDF
Abstract
Cecal abrasion in mice is a reliable model to study abdominal adhesions, which can be ameliorated using the MEK1/2 inhibitor trametinib. While blocking adhesion formation at the cell and molecular levels, trametinib, at the therapeutic doses utilized, did not impair the wound healing at the laparotomy site.
Related Topics
Health Sciences Medicine and Dentistry Surgery
Authors
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