| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8835572 | Journal of Surgical Research | 2018 | 9 Pages |
Abstract
Low dose of hydrocortisone is a mandatory adjunctive to antimicrobial therapy in a rat model of septic shock after bilateral adrenalectomy. The mechanism of action is related to reversal of sepsis-induced immunosuppression through interaction with histone deacetylases and de novo DNA methyltransferases.
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Authors
Triantafyllos MD, Stefanie MD, Sebastien MD, PhD, Ralf A. PhD, Konstantina MD, PhD, Evangelos J. MD, PhD, Michael MD, PhD, Ioannis M. MD, PhD,